Organizational Committee:

Dr. Arturo Ayon
Dept. of Physics and Astronomy at UTSA
 

Dr. Madhavrao (Rao) Govindaraju
SAI Global Technologies, Inc
 

Dr. Randolph D. Glickman
University of Texas Health Science Center San Antonio
 

Dr. John Grillo
Academic Workforce Programs at NVC
 

Dr. Kelly Nash
Dept. of Physics and Astronomy at UTSA
 

Dr. Vasiliki (Vicky) Zorbas Poenitzsch
Southwest Research Institute
 

Dr. Arturo Ponce
Depart. of Physics and Astronomy at UTSA

Dr. Bharathi Subramaniasiva
Texas Sustainable Energy Research Institute, UTSA
 

Dr. Wilson Terrell
Dept. of Engineering Sciences at Trinity University
 

Dr. Walt Trybula
Texas State University, San Marcos & Trybula Foundation, Inc., Austin
 

Dr. Stephen Wellinghoff
Southwest Research Institute
 

Dr. Miguel Yacaman
Dept. of Physics and Astronomy at UTSA
 

Dr. Qiaoying Joy Zhou
Academic Workforce Programs at Northwest Vista College
 

 

San Antonio Nano-Technology Forum (SANTF)

SANTF Networking Dinner Series

Clinical Development of Rhenium Nanoliposomes for Glioblastoma

Date: Wednesday, May 25, 2016

Time: 6:00 – 9:00 PM

Speaker:

Dr. Andrew Brenner

Associate Professor of Medicine, Neurology, and Neuro-Surgery, S & B Kolitz/CTRC-Zachry Endowed Chair Neuro-Oncology Research, UTHSCSA

ABSTRACT:

The therapeutic 186RNL is BMEDA-chelated 186Re-nanoliposomes (186RNL), which is being developed for the treatment of cancer, particularly glioblastoma multiforme (GBM). The liposomes are composed of a lipid bilayer of distearoylphosphatidylcholine and cholesterol, and confers drug delivery control on the active ingredient, BMEDA chelated 186Re. This then permits the delivery of 186Re radiation of high specific activity which is retained within the tumor. Although 186RNL has potential applications for multiple solid tumor types, the initial development is for treatment of glioblastoma. Primary glioblastoma is the most common and most aggressive type of primary malignant brain tumor. Presentation will focus on the preclinical data in GBM, the IND process to move into humans, and ongoing collaborations to allow administration by convection enhanced delivery.

Speaker Biography

Dr. Brenner is a medical oncologist and tumor biologist with an interest in drug development for the management of primary brain tumors and breast neoplasms. At the basic research level, his interests are in developing novel therapeutics for the treatment of malignancy. In particular, glioblastoma represents both a clinical challenge and a model neoplasm for studying the impact of hypoxia on neovascularization, and the mechanisms by which tumor cells develop resistance. To this end his research group has developed a number of animal models which allow the direct visualization of the hypoxic microenvironment and the vasculature. He has used animal models to assess the impact of different therapies on animal survival, and in particular the means of tumor adaptation. Many of these studies have resulted in clinical trials in patients which currently span through phase 2 with a phase 3 planned.

Venue:

Yaya’s Thai Restaurant

8085 Callaghan Rd

San Antonio, Texas 78230

 

Please RSVP to: info@santf.net on or before May 23, 2016. Please check our website (www.santf.net) for complete program details and upcoming meeting schedule.

Note: *Average cost of dinner is $12-$18. Attendees will need to purchase their dinner.

Flyer for this presentation is not available.

 

SANTF Purpose:

SANTF aims to provide participants with information on the state of nanotechnology research in Greater San Antonio institutions, presents trends in industry and research universities, informs innovative applications of nanotechnology, information related to current work in progress towards establishing national skills standards, details the involvement and support of national professional societies, and the current technician education programs supported by the National Science Foundation (NSF). The newly formed SANTF strives to build stronger communication and networking opportunities between educational and private businesses, both regionally and nationally; to solidify pipelines in education and stimulate job creation in the Greater San Antonio area in the field of nanotechnology and STEM related fields.    

Mission:

SANTF brings together researchers, innovators, entrepreneurs, and companies in the Greater San Antonio area working in the areas of nanomaterials and nanotechnology to showcase innovations related to the development and application of nanotechnology and nanomaterials. 

Goal:

Establish a venue for local researchers, early-stage investors, venture capitalists, and industry leaders to gather and discuss developments in nanotechnology and its applications in the areas of Biomaterials, Energy, Clean Technology, and Sustainability.  

 SANTF brings together major technology players in the area to form strong alliances among the researchers at the University of Texas at San Antonio (UTSA), University of Texas Health Science Center at San Antonio (UTHSCSA), Southwest Research Institute (SwRI), Texas Biomedical Research Institute, Alamo Community Colleges, Trinity University, Texas State University in San Marcos, and other educational institutions. SANTF promotes intellectual creativity in the area of nanotechnology that will create a strong nanotechnology base in San Antonio.    

 The forum is expected to spur productive collaborations among the researchers in Greater San Antonio area and promote innovations leading to scientific discoveries and engineering innovations.  SANTF is committed to enhancing San Antonio’s nanotechnology future and establishing the Alamo City as a global leader in nanotechnology.  

Flyers for Past Luncheons: